Thus the greater the kinetic energy of the molecules in a system, the greater is the resulting chemical potential energy when two molecules collide.
Ionizable side groups located in the active site must have a certain charge for the enzyme to bind its substrate.
Temperature optimum of an enzyme Given the above considerations, each enzyme has a temperatuare range in which a maximal rate of reaction is achieved. While higher temperatures do increase the activity of enzymes and the rate of reactions, enzymes are still proteins, and as with all proteins, temperatures above degrees Fahrenheit, 40 degrees Celsius, will start to break them down.
All enzymes work on contact, so when one of these enzymes comes in contact with the right substrate, it starts to work immediately. Like all proteins, enzymes are linear chains of amino acids that fold to produce a three-dimensional structure.
Thus the lower the kinetic energy, the lower the temperature of the system andlikewise, the higher the kinetic energy, the greater the temperature of the system.
The sequence of the amino acids specifies the structure which in turn determines the catalytic activity of the enzyme.